July plans? How about free art, comedy and hula hooping?


Want to get into the Phillips Collection, take a hula hooping class, or watch a comedy show – all for FREE? Check out Himmelfarb’s DC Study Break Guide for July!


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Can genetic information catch a killer?  And, cost you your privacy?

600px-ONS_compositesCan genetic information catch a killer?  And, cost you your privacy?

A recent essay published the New England Journal of Medicine explores the value and potential societal costs posed by access to private genetic information.  In Sociogenetic Risks — Ancestry DNA Testing, Third-Party Identity, and Protection of Privacy, Dr. Thomas May explores the tension between the utility of genetic information and risks to privacy posed by individuals, including adoptees, seeking to identify genetic relatives, the limitations of the Genetic Information Nondiscrimination Act (GINA), and the effect on large scale population studies such as the National Institute of Health’s All of Us initiative. 
To learn more about these issues and other genetics topics, explore the Genetics Journal Club and Himmelfarb Library‘s resources including:
  1. May T. Sociogenetic Risks – Ancestry DNA Testing, Third-Party Identity, and Protection of Privacy. N Engl J Med. 2018 Jun 20. doi: 10.1056/NEJMp1805870. [Epub ahead of print] PubMed PMID: 29924688. 
  2. Beamer LC. Ethics and Genetics: Examining a Crossroads in Nursing Through a Case Study
. Clin J Oncol Nurs. 2017 Dec 1;21(6):730-737. doi: 10.1188/17.CJON.730-737. PubMed PMID: 29149121. 
  3. Molnár-Gábor F, Lueck R, Yakneen S, Korbel JO. Computing patient data in the cloud: practical and legal considerations for genetics and genomics research in Europe and internationally. Genome Med. 2017 Jun 20;9(1):58. doi: 10.1186/s13073-017-0449-6. Review. PubMed PMID: 28633659; PubMed Central PMCID: PMC5477758. 
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Did you miss Himmelfarb Library’s 2018 Art Show?

AS2018_09_Lisa_Anderson__Porto_Sao_Bento_watermarkedDid you miss Himmelfarb Library‘s 2018 Art Show?  While the show is no longer physically in Himmelfarb Library, images of the art are available via the Health Science Research Commons.

The Health Sciences Research Commons (HSRC) is an online repository for gathering, archiving, and disseminating the material produced by GW’s Milken Institute School of Public Health, the School of Medicine and Health Sciences, and the School of Nursing.  The HSRC can be searched or browsed by school, author, or collection.
Check out the Himmelfarb Library Annual Art Show 2018 collection including  Porto São Bento, a photography by Lisa Anderson, George Washington University.
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Can being a Washington Capitals’ fan make you HAPPIER?

WashCapsAs the Washington Capitals’ winning record brings them closer to the Stanley Cup, Himmelfarb Library looks to the health sciences literature to assess if being a Washington Capitals’ fan can make you happier.

In this article, researchers explored the relationship of emotional expression with group membership.  Extrapolating from that data, we suggest that being a Washington Capitals fan will make you happier.


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Outdoor films, waterfront workouts, folklife & more!

June 2018 DC Study Guide Events

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Between fatalism and denial: living with a genetic diagnosis

puzzleIn the recent NEJM essay p53 and me, Shekinah N.C. Elmore describes the experience of living with a genetic diagnosis as “flying between fatalism and denial”.  Dr. Elmore was diagnosed with Li–Fraumeni syndrome during her 1st year of medical school having already survived childhood rhabdomyosarcoma and simultaneous diagnoses of breast and lung cancer as an adult.  Dr. Elmore explores what it means in her life to have this genetic knowledge, how it affects her life,  and what types of information would help her and others undergoing genetic testing in the future.

To learn more about genetic testing, genetic counseling, Li–Fraumeni syndrome, and other genetics topics, explore the Genetics Journal Club and Himmelfarb Library‘s resources including:

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Gene therapy for transfusion-dependent beta thalassemia patients?

Can gene therapy eliminate the need for blood transfusions for patients with transfusion-dependent β thalassemia?

This article reports the results of two phase 1-2 studies studied on the use of a gene therapy.  In these studies, patients with transfusion-depenent β-thalassemia received gene therapy to assess if this therapy would substitute for the standard therapy, red-cell blood transfusions.  The researchers were assessing both the safety and the efficacy of this gene therapy.  You can read the results of this study in the New England Journal of Medicine.

Thompson, A. A., Walters, M. C., Kwiatkowski, J., Rasko, J. E., Ribeil, J. A., Hongeng, S., … & Moshous, D. (2018). Gene therapy in patients with transfusion-dependent β-thalassemiaNew England Journal of Medicine378(16), 1479-1493.

To learn more about this area of gene therapy, explore additional readings from Himmelfarb Library’s full-text collection:

  • Boulad F, Mansilla-Soto J, Cabriolu A, Rivière I, Sadelain M. Gene Therapy and
    Genome Editing
    . Hematol Oncol Clin North Am. 2018 Apr;32(2):329-342. doi:
    10.1016/j.hoc.2017.11.007. Epub 2018 Jan 9. Review. PubMed PMID: 29458735.
  • Ferrari G, Cavazzana M, Mavilio F. Gene Therapy Approaches to
    . Hematol Oncol Clin North Am. 2017 Oct;31(5):835-852. doi:
    10.1016/j.hoc.2017.06.010. Review. PubMed PMID: 28895851.
  • Glaser A, McColl B, Vadolas J. The therapeutic potential of genome editing for
    . F1000Res. 2015 Dec 11;4. pii: F1000 Faculty Rev-1431. doi:
    10.12688/f1000research.7087.1. eCollection 2015. Review. PubMed PMID: 26918126;
    PubMed Central PMCID: PMC4753996.

Explore more of Himmelfarb Library’s genetics collection by checking out:

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