Lexicomp & Off-Label Drug Information

LexicompLexicomp has integrated information about off-label drug information into their drug information.  Lexicomp users will now find a ‘Use: Off-Label’ field in drug monographs.  This new field provides information on the off-label uses for the drug as well as an evidence rating.  For example, the drug monograph on Montelukast (Singulair) includes this information on off-label use:

  • Urticaria (nonsteroidal anti-inflammatory drug–induced)Level of Evidence [B]
  • Data from a double-blind, placebo-controlled comparison of montelukast and cetirizine in patients with chronic urticaria and intolerance to food additives and/or aspirin supports the use of montelukast in the treatment of patients experiencing urticaria related to the use of nonsteroidal anti-inflammatory drugs (Pacor, 2001).

Lexicomp is available via Himmelfarb Library‘s homepage and can be accessed from both on- and off-campus locations.  Himmelfarb Library also provides access to Lexicomp as an app which can be downloaded for free by GW affiliates via the Library’s App Shelf.

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